PLK2 Antibody / Polo-like kinase 2 / SNK

Contact us
NSJ Bioreagents
Product Code: NSJ-F54916
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54916-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54916-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the Polo-like kinase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 3
Western blot testing of human 1) 293T/17 and 2) HeLa cell lysate with Polo-like kinase 2 antibody. Predicted molecular weight ~78 kDa.
2 / 3
Western blot testing of human 1) Jurkat and 2) CCRF-CEM cell lysate with Polo-like kinase 2 antibody. Predicted molecular weight ~78 kDa.
3 / 3
IHC testing of FFPE human breast carcinoma tissue with Polo-like kinase 2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
❮❯

Western blot testing of human 1) 293T/17 and 2) HeLa cell lysate with Polo-like kinase 2 antibody. Predicted molecular weight ~78 kDa.
Western blot testing of human 1) Jurkat and 2) CCRF-CEM cell lysate with Polo-like kinase 2 antibody. Predicted molecular weight ~78 kDa.
IHC testing of FFPE human breast carcinoma tissue with Polo-like kinase 2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

Documents

Further Information

Application Details :
Western blot: 1:500-1:1000, Immunohistochemistry (FFPE): 1:50-1:100
Description:
Plks (polo-like kinases) encode serine/threonine kinases that are closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo-like kinases, which include Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk (for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cell proliferation. Plk protein accumulates in the cell during S and G2 phases of the cell cycle, and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk are immediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 375-406 from the human protein was used as the immunogen for the Polo-like kinase 2 antibody.
Limitation:
This Polo-like kinase 2 antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Antigen affinity purified
Species Reactivity :
Human
Uniprot #:
Q9NYY3