GSN Antibody / Gelsolin

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NSJ Bioreagents
Product Code: NSJ-F54920
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54920-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54920-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the GSN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 4
Flow cytometry testing of human A375 cells with GSN antibody; Blue=isotype control, Green= GSN antibody.
2 / 4
IHC testing of FFPE human skeletal muscle tissue with GSN antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
3 / 4
Western blot testing of 1) human plasma, 2) human HeLa, 3) mouse spleen and 4) rat kidney lysate with GSN antibody. Predicted molecular weight: 81-86 kDa (multiple isoforms).
4 / 4
Western blot testing of human MCF7 cell lysate with GSN antibody. Predicted molecular weight: 81-86 kDa (multiple isoforms).
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Flow cytometry testing of human A375 cells with GSN antibody; Blue=isotype control, Green= GSN antibody.
IHC testing of FFPE human skeletal muscle tissue with GSN antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Western blot testing of 1) human plasma, 2) human HeLa, 3) mouse spleen and 4) rat kidney lysate with GSN antibody. Predicted molecular weight: 81-86 kDa (multiple isoforms).
Western blot testing of human MCF7 cell lysate with GSN antibody. Predicted molecular weight: 81-86 kDa (multiple isoforms).

Documents

Further Information

Application Details :
Western blot: 1:1000-1:2000, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE): 1:50-1:100
Description:
GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this protein are a cause of familial amyloidosis Finnish type (FAF).
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 230-259 from the human protein was used as the immunogen for the GSN antibody.
Limitation:
This GSN antibody is available for research use only.
Localization:
Cytoplasmic, secreted
Purity:
Purified
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P06396