HER2 Antibody / ErbB2 / C-terminal region

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NSJ Bioreagents
Product Code: NSJ-F54939
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54939-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54939-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the ErbB2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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Western blot testing of human SK-BR-3 cell lysate with ErbB2 antibody. Expected molecular weight: 139-185 kDa depending on glycosylation level.
2 / 4
Western blot testing of human T-47D cell lysate with ErbB2 antibody. Expected molecular weight: 139-185 kDa depending on glycosylation level.
3 / 4
Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with ErbB2 antibody.
4 / 4
IHC testing of FFPE human breast cancer tissue with ErbB2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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Western blot testing of human SK-BR-3 cell lysate with ErbB2 antibody. Expected molecular weight: 139-185 kDa depending on glycosylation level.
Western blot testing of human T-47D cell lysate with ErbB2 antibody. Expected molecular weight: 139-185 kDa depending on glycosylation level.
Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with ErbB2 antibody.
IHC testing of FFPE human breast cancer tissue with ErbB2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

Documents

Further Information

Application Details :
Immunohistochemistry (FFPE): 1:50-1:100, Western blot: 1:500-1:1000
Description:
ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, althought neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 1206-1236 from the human protein was used as the immunogen for the ErbB2 antibody.
Limitation:
This ErbB2 antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
P04626