IGF1R Antibody / Insulin like growth factor 1 receptor

Contact us
NSJ Bioreagents
Product Code: NSJ-F54940
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54940-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54940-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the IGF1 Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 3
Western blot testing of 1) human 293T, 2) human A431, 3) mouse C2C12, 4) rat C6, 5) human HeLa and 6) mouse NIH 3T3 cell lysate with IGF1 Receptor antibody. Expected molecular weight: ~69 kDa (unglycosylated beta chain) up to ~200 kDa (glycosylated pro-form).
2 / 3
Western blot testing of human SK-BR-3 cell lysate with IGF1 Receptor antibody. Expected molecular weight: ~69 kDa (unglycosylated beta chain) up to ~200 kDa (glycosylated pro-form).
3 / 3
IHC testing of FFPE human cancer tissue with IGF1 Receptor antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
❮❯

Western blot testing of 1) human 293T, 2) human A431, 3) mouse C2C12, 4) rat C6, 5) human HeLa and 6) mouse NIH 3T3 cell lysate with IGF1 Receptor antibody. Expected molecular weight: ~69 kDa (unglycosylated beta chain) up to ~200 kDa (glycosylated pro-form).
Western blot testing of human SK-BR-3 cell lysate with IGF1 Receptor antibody. Expected molecular weight: ~69 kDa (unglycosylated beta chain) up to ~200 kDa (glycosylated pro-form).
IHC testing of FFPE human cancer tissue with IGF1 Receptor antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

Documents

Further Information

Application Details :
Immunohistochemistry (FFPE): 1:50-1:100, Western blot: 1:500-1:1000
Description:
The IGF1 receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 1335-1366 from the human protein was used as the immunogen for the IGF1 Receptor antibody.
Limitation:
This IGF1 Receptor antibody is available for research use only.
Purity:
Purified
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
P08069