IRS2 Antibody / Insulin receptor substrate 2

Contact us
NSJ Bioreagents
Product Code: NSJ-F54949
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54949-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54949-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the Insulin receptor substrate 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 4
Western blot testing of human HeLa cell lysate with Insulin receptor substrate 2 antibody. Predicted molecular weight ~137 kDa.
2 / 4
Western blot testing of human HEK293 cell lysate with Insulin receptor substrate 2 antibody. Predicted molecular weight ~137 kDa.
3 / 4
Immunofluorescent staining of fixed and permeabilized human HeLa cells with Insulin receptor substrate 2 antibody (green) and anti-Actin (red).
4 / 4
IHC testing of FFPE human hepatocellular carcinoma tissue with Insulin receptor substrate 2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
❮❯

Western blot testing of human HeLa cell lysate with Insulin receptor substrate 2 antibody. Predicted molecular weight ~137 kDa.
Western blot testing of human HEK293 cell lysate with Insulin receptor substrate 2 antibody. Predicted molecular weight ~137 kDa.
Immunofluorescent staining of fixed and permeabilized human HeLa cells with Insulin receptor substrate 2 antibody (green) and anti-Actin (red).
IHC testing of FFPE human hepatocellular carcinoma tissue with Insulin receptor substrate 2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

Documents

Further Information

Application Details :
Western blot: 1:500-1:1000, Immunofluorescence: 1:10-1:50, Immunohistochemistry (FFPE): 1:50-1:100
Description:
Insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. This protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 1309-1338 from the human protein was used as the immunogen for the Insulin receptor substrate 2 antibody.
Limitation:
This Insulin receptor substrate 2 antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Purified
Species Reactivity :
Human
Uniprot #:
Q9Y4H2