MEK2 Antibody / MAP2K2

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NSJ Bioreagents
Product Code: NSJ-F54958
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54958-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54958-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the MAP2K2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 4
Western blot testing of human 1) HeLa and 2) MOLT4 cell lysate with MAP2K2 antibody. Expected molecular weight: 45-50 kDa.
2 / 4
Western blot testing of human Y79 cell lysate with MAP2K2 antibody. Expected molecular weight: 45-50 kDa.
3 / 4
Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with MAP2K2 antibody.
4 / 4
IHC testing of FFPE human prostate carcinoma tissue with MAP2K2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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Western blot testing of human 1) HeLa and 2) MOLT4 cell lysate with MAP2K2 antibody. Expected molecular weight: 45-50 kDa.
Western blot testing of human Y79 cell lysate with MAP2K2 antibody. Expected molecular weight: 45-50 kDa.
Western blot testing of 1) non-transfected and 2) transfected 293 cell lysate with MAP2K2 antibody.
IHC testing of FFPE human prostate carcinoma tissue with MAP2K2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

Documents

Further Information

Application Details :
Immunohistochemistry (FFPE): 1:10-1:50, Western blot: 1:500-1:1000
Description:
MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 200-229 from the human protein was used as the immunogen for the MAP2K2 antibody.
Limitation:
This MAP2K2 antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Antigen affinity purified
Species Reactivity :
Human
Uniprot #:
P36507