IFNAR1 Antibody / Interferon alpha receptor 1

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NSJ Bioreagents
Product Code: NSJ-F54976
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F54976-0.08ML0.08 ml£260.00
Quantity:
NSJ-F54976-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the Interferon alpha receptor 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 3
IHC testing of FFPE human brain tissue with Interferon alpha receptor 1 antibody. HIER: steam section in pH9 EDTA buffer for 20 min and allow to cool prior to staining.
2 / 3
Western blot testing of human 1) HeLa, 2) 293T, 3) Jurkat, 4) brain, 5) heart and 6) K562 cell lysate with Interferon alpha receptor 1 antibody. Expected molecular weight: 64-135 kDa depending on glycosylation level.
3 / 3
Flow cytometry testing of fixed and permeabilized human K562 cells with Interferon alpha receptor 1 antibody; Blue=isotype control, Green= Interferon alpha receptor 1 antibody.
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IHC testing of FFPE human brain tissue with Interferon alpha receptor 1 antibody. HIER: steam section in pH9 EDTA buffer for 20 min and allow to cool prior to staining.
Western blot testing of human 1) HeLa, 2) 293T, 3) Jurkat, 4) brain, 5) heart and 6) K562 cell lysate with Interferon alpha receptor 1 antibody. Expected molecular weight: 64-135 kDa depending on glycosylation level.
Flow cytometry testing of fixed and permeabilized human K562 cells with Interferon alpha receptor 1 antibody; Blue=isotype control, Green= Interferon alpha receptor 1 antibody.

Documents

Further Information

Application Details :
Western blot: 1:500-1:1000, Flow cytometry: 1:25 (1x10e6 cells), Immunohistochemistry (FFPE): 1:50-1:100
Description:
IFNAR1 is the receptor for interferons alpha and beta. Binding to type I IFNs triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and IFNR alpha-and beta-subunits themselves.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 162-188 from the human protein was used as the immunogen for the Interferon alpha receptor 1 antibody.
Limitation:
This Interferon alpha receptor 1 antibody is available for research use only.
Localization:
Cytoplasmic, cell membrane
Purity:
Antigen affinity purified
Species Reactivity :
Human
Uniprot #:
P17181