Mu-type Opioid Receptor Antibody / OPRM1

NSJ Bioreagents
Product Code: NSJ-F55020
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F55020-0.08ML0.08 ml£260.00
Quantity:
NSJ-F55020-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the Mu-type Opioid Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 4
Western blot testing of mouse heart tissue lysate with Mu-type Opioid Receptor antibody. Predicted molecular weight ~45 kDa.
2 / 4
Western blot testing of human MDA-MB-231 cell lysate with Mu-type Opioid Receptor antibody. Predicted molecular weight ~45 kDa.
3 / 4
IHC testing of FFPE human brain tissue with Mu-type Opioid Receptor antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
4 / 4
Flow cytometry testing of human K562 cells with Mu-type Opioid Receptor antibody; Blue=isotype control, Green= Mu-type Opioid Receptor antibody.

Western blot testing of mouse heart tissue lysate with Mu-type Opioid Receptor antibody. Predicted molecular weight ~45 kDa.
Western blot testing of human MDA-MB-231 cell lysate with Mu-type Opioid Receptor antibody. Predicted molecular weight ~45 kDa.
IHC testing of FFPE human brain tissue with Mu-type Opioid Receptor antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Flow cytometry testing of human K562 cells with Mu-type Opioid Receptor antibody; Blue=isotype control, Green= Mu-type Opioid Receptor antibody.

Further Information

Application Details :
Western blot: 1:500-1:1000, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE): 1:10-1:50
Description:
OPRM1 is the mu opioid receptor, which is the primary site of action for the most commonly used opioids, including morphine, heroin, fentanyl, and methadone. It is also the primary receptor for endogenous opioid peptides beta-endorphin and the enkephalins. The OPRM1 receptor is a membrane of the G protein-coupled receptor family (Bond et al., 1998). There are at least 3 types of opioid receptors, mu, kappa, and delta, each with a distinct pharmacologic profile.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 161-187 from the human protein was used as the immunogen for the Mu-type Opioid Receptor antibody.
Limitation:
This Mu-type Opioid Receptor antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Antigen affinity purified
Species Reactivity :
Human, Mouse
Uniprot #:
P35372