Xanthine Oxidase Antibody / XDH

NSJ Bioreagents
Product Code: NSJ-F55029
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F55029-0.08ML0.08 ml£260.00
Quantity:
NSJ-F55029-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the XDH antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 4
Western blot testing of human fetal liver tissue lysate with XDH antibody. Predicted molecular weight ~146 kDa.
2 / 4
Western blot testing of mouse lung tissue lysate with XDH antibody. Predicted molecular weight ~146 kDa.
3 / 4
IHC testing of FFPE human hepatocellular carcinoma tissue with XDH antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
4 / 4
Flow cytometry testing of human MDA-MB-231 cells with XDH antibody; Blue=isotype control, Green= XDH antibody.

Western blot testing of human fetal liver tissue lysate with XDH antibody. Predicted molecular weight ~146 kDa.
Western blot testing of mouse lung tissue lysate with XDH antibody. Predicted molecular weight ~146 kDa.
IHC testing of FFPE human hepatocellular carcinoma tissue with XDH antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Flow cytometry testing of human MDA-MB-231 cells with XDH antibody; Blue=isotype control, Green= XDH antibody.

Further Information

Application Details :
Western blot: 1:500-1:1000, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE): 1:10-1:50
Description:
XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 206-234 from the human protein was used as the immunogen for the XDH antibody.
Limitation:
This XDH antibody is available for research use only.
Localization:
Cytoplasmic, secreted
Purity:
Antigen affinity purified
Species Reactivity :
Human, Mouse
Uniprot #:
P47989