FANCC Antibody / Fanconi anemia group C protein

NSJ Bioreagents
Product Code: NSJ-F55035
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F55035-0.08ML0.08 ml£260.00
Quantity:
NSJ-F55035-0.4ML0.4 ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunofluorescence (IF)
  • Immunohistochemistry- Paraffin Embedded (IHC-P)
  • Western Blot (WB)
Storage:
Aliquot the FANCC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 4
Western blot testing of human 1) HepG2 and 2) HL60 cell lysate with FANCC antibody. Predicted molecular weight ~63 kDa.
2 / 4
Immunofluorescent staining of human U-251 cells with FANCC antibody (green), DAPI nuclear stain (blue) and anti-Actin (red).
3 / 4
IHC testing of FFPE human testis tissue with FANCC antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
4 / 4
Flow cytometry testing of human HL60 cells with FANCC antibody; Blue=isotype control, Green= FANCC antibody.

Western blot testing of human 1) HepG2 and 2) HL60 cell lysate with FANCC antibody. Predicted molecular weight ~63 kDa.
Immunofluorescent staining of human U-251 cells with FANCC antibody (green), DAPI nuclear stain (blue) and anti-Actin (red).
IHC testing of FFPE human testis tissue with FANCC antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
Flow cytometry testing of human HL60 cells with FANCC antibody; Blue=isotype control, Green= FANCC antibody.

Further Information

Application Details :
Western blot: 1:500-1:1000, Immunofluorescence: 1:25, Flow cytometry: 1:10-1:50 (1x10e6 cells), Immunohistochemistry (FFPE): 1:50-1:100
Description:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This protein is for complementation group C.
Format :
Purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 527-555 from the human protein was used as the immunogen for the FANCC antibody.
Limitation:
This FANCC antibody is available for research use only.
Localization:
Cytoplasmic, nuclear
Purity:
Antigen affinity purified
Species Reactivity :
Human
Uniprot #:
Q00597