TGFB1 Antibody

NSJ Bioreagents
Product Code: NSJ-F55055
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-F55055-0.08ML0.08ml£260.00
Quantity:
NSJ-F55055-0.4ML0.4ml£502.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit Ig
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Aliquot the TGFB1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 1
Western blot testing of human 1) HepG2, 2) K562 and 3) Raji cell lysate using TGFB1 antibody. Predicted molecular weight: 44-50 kDa (precursor), ~25 kDa (active form).

Western blot testing of human 1) HepG2, 2) K562 and 3) Raji cell lysate using TGFB1 antibody. Predicted molecular weight: 44-50 kDa (precursor), ~25 kDa (active form).

Further Information

Application Details :
Western blot: 1:2000
Application Note:
Titration of the TGFB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Description:
TGFB1 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types. Many cells have TGFB receptors, and the protein positively and negatively regulates many other growth factors. The secreted protein is cleaved into a latency-associated peptide (LAP) and a mature TGFB1 peptide, and is found in either a latent form composed of a TGFB1 homodimer, a LAP homodimer, and a latent TGFB1-binding protein, or in an active form composed of a TGFB1 homodimer. The mature peptide may also form heterodimers with other TGFB family members. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease.
Format :
Antigen affinity purified
Formulation :
In 1X PBS, pH 7.4, with 0.09% sodium azide
Immunogen:
A portion of amino acids 22-50 from the human protein was used as the immunogen for this TGFB1 antibody.
Limitation:
This TGFB1 antibody is available for research use only.
Purity:
Antigen affinity
Species Reactivity :
Human
Uniprot #:
P01137