CD47 Antibody / IAP / Integrin Associated Protein

NSJ Bioreagents
Product Code: NSJ-V9272
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V9272-20UG20ug£264.00
Quantity:
NSJ-V9272-100UG100ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: CD47/6364R
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the recombinant CD47 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

1 / 2
IHC staining of FFPE human prostate carcinoma tissue with recombinant CD47 antibody (clone CD47/6364R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.~
2 / 2
SDS-PAGE analysis of purifie

IHC staining of FFPE human prostate carcinoma tissue with recombinant CD47 antibody (clone CD47/6364R). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.~
SDS-PAGE analysis of purifie

Further Information

Application Details :
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the recombinant CD47 antibody should be determined by the researcher.
Description:
Receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation. May play a role in membrane transport and/or integrin dependent signal transduction. May prevent premature elimination of red blood cells. May be involved in membrane permeability changes induced following virus infection. [UniProt]
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A portion of amino acids 18-135 from the human protein was used as the immunogen for the recombinant CD47 antibody.
Limitation:
This recombinant CD47 antibody is available for research use only.
Localization:
Cell surface, cytoplasmic
Purity:
Protein A/G affinity
Species Reactivity :
Human
Uniprot #:
Q08722