LEF1 Antibody / Lymphoid enhancer-binding factor 1 / TCF1 alpha

NSJ Bioreagents
Product Code: NSJ-V9285
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V9285-20UG20ug£264.00
Quantity:
NSJ-V9285-100UG100ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Recombinant Antibody
Antibody Clone: LEF1/422R
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the TCF1 alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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IHC staining of FFPE human lymph node cells (nuclear staining of non-germinal center) using TCF1 alpha antibody (clone LEF1/422R) at 2ug/ml.~
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Negative control: IHC staining of human brain tissue with TCF1 alpha antibody at 2ug/ml. HIER:

IHC staining of FFPE human lymph node cells (nuclear staining of non-germinal center) using TCF1 alpha antibody (clone LEF1/422R) at 2ug/ml.~
Negative control: IHC staining of human brain tissue with TCF1 alpha antibody at 2ug/ml. HIER:

Further Information

Application Details :
Immunohistochemistry (FFPE): 1-2ug/ml
Application Note:
Optimal dilution of the TCF1 alpha antibody should be determined by the researcher.
Description:
Lymphoid Enhancing Factor 1 (LEF1), also called T cell-specific transcription factor 1-alpha (TCF1 alpha) is a transcription factor that belongs to the TCF/LEF family. LEF1 participates as a regulator in Wnt signaling pathways. LEF1 is an important factor in lymphopoiesis and is expressed normally in T and pro-B cells but not expressed in mature B cells. Anti-LEF1 may be used as an aid for differentiation of chronic lymphocytic leukemia/small lymphocytic lymphoma from other small B cell lymphomas.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A portion of amino acids 100-200 was used as the immunogen for the TCF1 alpha antibody.
Limitation:
This TCF1 alpha antibody is available for research use only.
Localization:
Nucleus
Purity:
Protein A/G affinity
Species Reactivity :
Human
Uniprot #:
Q9UJU2