Estrogen Receptor alpha Antibody

NSJ Bioreagents
Product Code: NSJ-V8779
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-V8779-20UG20ug£264.00
Quantity:
NSJ-V8779-100UG100ug£534.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Mouse
Antibody Isotype: Mouse IgG2a, kappa
Antibody Clonality: Monoclonal
Antibody Clone: ESR1/420
Regulatory Status: RUO
Target Species: Human
Applications:
  • Fluorescence-activated cell sorting (FACS)
  • Immunofluorescence (IF)
Storage:
Aliquot the Estrogen Receptor alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Images

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SDS-PAGE analysis of purified, BSA-free Estrogen Receptor alpha antibody (ESR1/420) as confirmation of integrity and purity.

SDS-PAGE analysis of purified, BSA-free Estrogen Receptor alpha antibody (ESR1/420) as confirmation of integrity and purity.

Further Information

Application Details :
Flow cytometry: 1-2ug/million cells,Immunofluorescence: 1-2ug/ml
Application Note:
Optimal dilution of the Estrogen Receptor alpha antibody should be determined by the researcher.
Description:
This mAb is specific to ER alpha and shows minimal cross-reaction with other members of the family. ER is an important regulator of growth and differentiation in the mammary gland. Presence of ER in breast tumors indicates an increased likelihood of response to anti-estrogen (e.g. tamoxifen) therapy.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A portion of amino acids 290-560 was used as the immunogen for the Estrogen Receptor alpha antibody. The epitope of this mAb is between amino acids 300-550.
Limitation:
This Estrogen Receptor alpha antibody is available for research use only.
Localization:
Nuclear
Purity:
Protein A/G affinity
Species Reactivity :
Human
Uniprot #:
P03372