PAX5 Antibody

ELISA: 1-5ug/ml (order BSA-free format for coating)

Optimal dilution of the PAX5 antibody should be determined by the researcher.

The PAX5 gene is a member of the paired box (PAX)family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Recombinant full-length human PAX5 protein was used as the immunogen for the PAX5 antibody.

This PAX5 antibody is available for research use only.

Nuclear

Protein A/G affinity

Human

Q02548