BPIFB1 Antibody / LPLUNC1

ELISA (order BSA-free format for coating),Western blot: 1-2ug/ml,Immunohistochemistry (FFPE): 1-2ug/ml

Optimal dilution of the BPIFB1 antibody should be determined by the researcher.

The upper respiratory tract is the main place of entry for pathogens to invade the body, and early recognition of bacterial products in this region is crucial for host defense. Palate lung nasal epithelial clone PLUNC (or LUNX) is an airway specific secretory protein that is expressed in epithelial tissues and submucosal glands of the oral cavity and upper respiratory tract of humans, mice, rats and cows. PLUNC binds to lipopolysaccharide (LPS) in nasal lavage fluid (NLF) which points to its role in the inflammatory response of the upper airways after exposure to irritants. Decreased levels of PLUNC occur in the NLF of smokers and people who have been exposed to reactive epoxy chemicals, indicating that long-term exposure to airway irritants impairs the production of PLUNC in the upper respiratory tract. Abnormal expression of PLUNC may influence susceptibility to nasopharyngeal carcinoma in the Chinese population.

Purified

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide

Recombinant full-length human BPIFB1/LPLUNC1 protein was used as the immunogen for the BPIFB1 antibody.

This BPIFB1 antibody is available for research use only.

Secreted

Protein A/G affinity

Human

Q8TDL5