p120 Catenin Antibody / CTNND1 / Catenin delta 1
Code | Size | Price |
---|
NSJ-V9324-20UG | 20ug | £264.00 |
Quantity:
NSJ-V9324-100UG | 100ug | £534.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Mouse
Antibody Isotype: Mouse IgG2b, kappa
Antibody Clonality: Monoclonal
Antibody Clone: CTNND1/4501
Regulatory Status: RUO
Target Species: Human
Application: Immunohistochemistry- Paraffin Embedded (IHC-P)
Storage:
Aliquot the Delta 1 Catenin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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Further Information
Application Details :
Immunohistochemistry (FFPE): 2-4ug/ml
Application Note:
Optimal dilution of the Delta 1 Catenin antibody should be determined by the researcher.
Description:
Alpha-catenin and beta-catenin bind to the intracellular domain of E-cadherin while p120 catenin (delta-1-catenin) binds E-cadherin at a juxta-membrane site. The complex stabilizes tight junctions. In the cell, delta-1-catenin localized to the E-cadherin/catenins cell adhesion complex, directly associates with cytoplasmic C-terminus of E-cadherin and may similarly interact with other cadherins.
Format :
Purified
Formulation :
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Immunogen:
A portion of amino acids 138-276 was used as the immunogen for the Delta 1 Catenin antibody.
Limitation:
This Delta 1 Catenin antibody is available for research use only.
Localization:
Cell Surface, Cytoplasm
Purity:
Protein A/G affinity
Species Reactivity :
Human
Uniprot #:
O60716