G6PD Antibody / Glucose-6-phosphate dehydrogenase

Western blot: 1:500-1:2000

Optimal dilution of the G6PD antibody should be determined by the researcher.

The G6PD gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human Glucose 6 Phosphate Dehydrogenase / G6PD was used as the immunogen for the G6PD antibody.

This G6PD antibody is available for research use only.

Affinity purified

Human

P11413