Neurofilament Antibody (-Heavy) / NF-H / NEFH

Western blot: 1:500-1:2000

Optimal dilution of the NF-H antibody should be determined by the researcher.

Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. The NEFH gene encodes the heavy neurofilament protein. This protein is commonly used as a biomarker of neuronal damage and susceptibility to amyotrophic lateral sclerosis (ALS) has been associated with mutations in this gene. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human Neurofilament Heavy / NF-H / NEFH was used as the immunogen for the NF-H antibody.

This NF-H antibody is available for research use only.

Affinity purified

Human

P12036