ACE Antibody / Angiotensin-Converting Enzyme

Western blot: 1:500-1:1000

Optimal dilution of the ACE antibody should be determined by the researcher.

The ACE gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, and two most abundant spliced variants encode the somatic form and the testicular form, respectively, that are equally active. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human Angiotensin-Converting Enzyme was used as the immunogen for the ACE antibody.

This ACE antibody is available for research use only.

Affinity purified

Human, Mouse

P12821