Ku80 Antibody / XRCC5
| Code | Size | Price |
|---|
| NSJ-RQ5399-100ul | 100 ul | £535.00 |
Quantity:
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Overview
Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Monoclonal
Antibody Clone: FAE-24
Regulatory Status: RUO
Target Species: Human
Application: Western Blot (WB)
Storage:
Store the Ku80 antibody at -20oC.
Documents
Further Information
Application Details :
Western blot: 1:5000-1:10000
Application Note:
Optimal dilution of the Ku80 antibody should be determined by the researcher.
Description:
The protein encoded by the XRCC5 gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. [RefSeq]
Format :
Purified
Formulation :
Antibody in PBS with 0.02% sodium azide and 50% glycerol
Immunogen:
A synthetic peptide specific to human Ku80 / XRCC5 was used as the immunogen for the Ku80 antibody.
Limitation:
This Ku80 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
P13010