MMP9 Antibody / Matrix metalloproteinase-9

Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:50-1:200

Optimal dilution of the MMP9 antibody should be determined by the researcher.

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human MMP9 was used as the immunogen for the MMP9 antibody.

This MMP9 antibody is available for research use only.

Cytoplasmic, nuclear, secreted

Affinity purified

Human, Rat

P14780