CD44 Antibody / HCAM

Western blot: 1:500-1:2000,Immunohistochemistry (FFPE): 1:50-1:200

Optimal dilution of the CD44 antibody should be determined by the researcher.

The protein encoded by the CD44 gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human CD44 was used as the immunogen for the CD44 antibody.

This CD44 antibody is available for research use only.

Cell surface, cytoplasmic

Affinity purified

Human

P16070