Integrin beta 4 Antibody / ITGB4 / CD104

Western blot: 1:500-1:2000

Optimal dilution of the CD104 antibody should be determined by the researcher.

Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. The ITGB4 gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. [RefSeq]

Purified

Antibody in PBS with 0.02% sodium azide and 50% glycerol

A synthetic peptide specific to human Integrin beta 4 / ITGB4 was used as the immunogen for the CD104 antibody.

This CD104 antibody is available for research use only.

Affinity purified

Human, Mouse

P16144