BMAL1 Antibody / ARNTL

NSJ Bioreagents
Product Code: NSJ-RQ5563
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ5563-100ug100 ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species:
  • Human
  • Mouse
  • Rat
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
After reconstitution, the BMAL1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Images

1 / 2
Western blot testing of 1) rat heart and 2) mouse heart lysate with BMAL1 antibody. Predicted molecular weight ~69 kDa.
2 / 2
Western blot testing of human 1) U-2 OS, 2) ThP-1, 3) PC-3 and 4) K562 cell lysate with BMAL1 antibody. Predicted molecular weight ~69 kDa.

Western blot testing of 1) rat heart and 2) mouse heart lysate with BMAL1 antibody. Predicted molecular weight ~69 kDa.
Western blot testing of human 1) U-2 OS, 2) ThP-1, 3) PC-3 and 4) K562 cell lysate with BMAL1 antibody. Predicted molecular weight ~69 kDa.

Further Information

Application Details :
Western blot: 0.25-0.5ug/ml,Direct ELISA: 0.1-0.5ug/ml
Application Note:
Optimal dilution of the BMAL1 antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
Description:
Aryl hydrocarbon receptor nuclear translocator-like protein 1 is protein that in humans is encoded by the ARNTL gene. The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
A human recombinant protein (amino acids R116-E447) was used as the immunogen for the BMAL1 antibody.
Limitation:
This BMAL1 antibody is available for research use only.
Purity:
Affinity purified
Species Reactivity :
Human, Mouse, Rat
Uniprot #:
O00327