MAVS Antibody (IPS-1)

NSJ Bioreagents
Product Code: NSJ-RQ6496
Product Group: Primary Antibodies
Supplier: NSJ Bioreagents
CodeSizePrice
NSJ-RQ6496-100ug100ug£535.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: Rabbit IgG
Antibody Clonality: Polyclonal
Regulatory Status: RUO
Target Species: Human
Applications:
  • Immunofluorescence (IF)
  • Western Blot (WB)
Storage:
After reconstitution, the MAVS antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Images

1 / 2
Immunofluorescent staining of FFPE human Caco-2 cells with MAVS antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
2 / 2
Western blot testing of human 1) HeLa and 2) Jurkat cell lysate with MAVS antibody. Expected molecular weight: 51-54 kDa (cleaved), 57 kDa (unmodified), 75 kDa (aggregated).

Immunofluorescent staining of FFPE human Caco-2 cells with MAVS antibody (green) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
Western blot testing of human 1) HeLa and 2) Jurkat cell lysate with MAVS antibody. Expected molecular weight: 51-54 kDa (cleaved), 57 kDa (unmodified), 75 kDa (aggregated).

Further Information

Application Details :
Western blot: 1-2ug/ml,Immunofluorescence: 5ug/ml
Application Note:
Optimal dilution of the MAVS antibody should be determined by the researcher.
Buffer:
Lyophilized from 1X PBS with 2% Trehalose
Description:
Mitochondrial antiviral-signaling protein (MAVS) is a protein that in humans is encoded by the MAVS gene. The protein is also known by the names VISA (virus-induced signaling adapter), IPS-1 and Cardif. This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral immunity.
Format :
Antigen affinity purified
Formulation :
0.5mg/ml if reconstituted with 0.2ml sterile DI water
Immunogen:
Amino acids DEVASVYQSYQPRTSDRPPDPLE from the human protein were used as the immunogen for the MAVS antibody.
Limitation:
This MAVS antibody is available for research use only.
Localization:
Cytoplasmic
Purity:
Affinity purified
Species Reactivity :
Human
Uniprot #:
Q7Z434