Tim-1 Antibody [3B3], Rabbit IgG

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ProSci
Product Code: PSI-24-599
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-24-599-0.2mg0.2mg£681.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG kappa
Antibody Clonality: Monoclonal
Antibody Clone: 3B3
Regulatory Status: RUO
Target Species: Mouse
Applications:
  • Agonism
  • Flow Cytometry
  • Immunofluorescence (IF)
  • Immunohistochemistry (IHC)
Shipping:
Blue Ice
Storage:
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Images

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<b> Surface plasmon resonance (SPR) sensorgram anti-TIM-1 (3B3 binding to TIM-1 Fc-fusion protein. </b> Binding of mouse TIM-1 Fc-fusion protein (Pr00227-1.9) to immbolised the r chimeric version of 3B3 (24-599). Pr00227-1.9 was injected and allowed to associate with 24-599 between 1080s and 1250s- before a dissociation phase between 1250s and 1800s. Pr00227-1.9 showed rapid binding to 24-599 and following ligand removal remained strongly bound. This suggests that 24-599 has a very high affinity for Pr00227-1.9.
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<b> Surface plasmon resonance (SPR) sensorgram anti-TIM-1 (3B3 binding to TIM-1 Fc-fusion protein. </b> Binding of mouse TIM-1 Fc-fusion protein (Pr00227-1.9) to immbolised the r chimeric version of 3B3 (24-599). Pr00227-1.9 was injected and allowed to associate with 24-599 between 1080s and 1250s- before a dissociation phase between 1250s and 1800s. Pr00227-1.9 showed rapid binding to 24-599 and following ligand removal remained strongly bound. This suggests that 24-599 has a very high affinity for Pr00227-1.9.

Documents

Further Information

Additional Names:
CD365, HAVcr-1, HAVCR1, Hepatitis A virus cellular receptor 1 homolog, Kidney injury molecule 1, KIM-1, T cell immunoglobulin and mucin domain-containing protein 1, T cell membrane protein 1, T-cell immunoglobulin and mucin domain containing 1, T-cell immunoglobulin mucin receptor 1, TIM-1, TIM1, TIMD-1
Buffer:
PBS with 0.02% Proclin 300.
Chimeric Use Statement:
This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2a format, for improved compatibility with existing reagents, assays and techniques.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
This antibody was raised by immunising female Lewis strain rats (Harlan Sprague-Dawley) subcutaneously with mouse TIM-1?Ig in complete Freund's adjuvant (CFA), followed by multiple 'boosting' with mouse TIM-1?Ig in PBS.
NCBI Gene ID #:
171283
NCBI Official Name:
hepatitis A virus cellular receptor 1
NCBI Official Symbol:
Havcr1
NCBI Organism:
Mus musculus
Research Area:
Immunology, Chemokines & Cytokines, Cell Cycle
Swissprot #:
Q5QNS5
User NOte:
For research use only.