COVID-19 & SARS-CoV S glycoprotein Antibody [CR3022], Human IgG1

ProSci
Product Code: PSI-24-805
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-24-805-0.2mg0.2mg£681.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Human
Antibody Isotype: IgG1 kappa
Antibody Clonality: Monoclonal
Antibody Clone: CR3022
Regulatory Status: RUO
Target Species: Virus
Applications:
  • Crystallography
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunofluorescence (IF)
  • Neutralisation
  • Surface Plasma Resonance
Shipping:
Blue Ice
Storage:
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Images

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<b> Binding curve of anti-COVID-19 & SARS-CoV S glycoprotein antibody CR3022 (24-805) to SARS-CoV-2 Spike Glycoprotein (S1)- Sheep Fc-Tag and SARS-CoV-2 Spike Glycoprotein (S2)- Sheep Fc-Tag from HEK293 cells. </b> ELISA plate coated with SARS-CoV-2 Spike Glycoprotein (S1)- Sheep Fc-Tag (blue line) or SARS-CoV-2 Spike Glycoprotein (S2)- Sheep Fc-Tag (orange line) from HEK293 cells (The Native Antigen Company) at concentrations of 5 ug/ml. A 3-fold serial dilution from 125 ng/ml was performed using 24-805. For detection- a 1:4000 dilution of HRP-lnti-human IgG antibody was used.
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<b> Binding curve of four different formats of anti-COVID-19 & SARS-CoV S glycoprotein antibody CR3022 (to SARS-CoV-2 Spike Glycoprotein domains S1 and S2 (His-Tag (Insect Cells)). </b> ELISA plate coated with SARS-CoV-2 Spike Glycoprotein (S1)- His-Tag (Insect Cells; grey line) and SARS-CoV-2 Spike Glycoprotein (S2)- His-Tag (Insect Cells; yellow line) (Native Antigen) at concentrations of 5 ug/ml. A 3-fold serial dilution from 41.6 ng/ml was performed using 24-805; from 370 ng/ml for 6.0 and from 10000 ng/ml for 5.0 and 1.0. Human IgM- human IgA and human IgG2 were HRP-conjugated and for the detection of human IgG1 a 1:4000 dilution of HRP-lnti-human IgG antibody was used.

<b> Binding curve of anti-COVID-19 & SARS-CoV S glycoprotein antibody CR3022 (24-805) to SARS-CoV-2 Spike Glycoprotein (S1)- Sheep Fc-Tag and SARS-CoV-2 Spike Glycoprotein (S2)- Sheep Fc-Tag from HEK293 cells. </b> ELISA plate coated with SARS-CoV-2 Spike Glycoprotein (S1)- Sheep Fc-Tag (blue line) or SARS-CoV-2 Spike Glycoprotein (S2)- Sheep Fc-Tag (orange line) from HEK293 cells (The Native Antigen Company) at concentrations of 5 ug/ml. A 3-fold serial dilution from 125 ng/ml was performed using 24-805. For detection- a 1:4000 dilution of HRP-lnti-human IgG antibody was used.
<b> Binding curve of four different formats of anti-COVID-19 & SARS-CoV S glycoprotein antibody CR3022 (to SARS-CoV-2 Spike Glycoprotein domains S1 and S2 (His-Tag (Insect Cells)). </b> ELISA plate coated with SARS-CoV-2 Spike Glycoprotein (S1)- His-Tag (Insect Cells; grey line) and SARS-CoV-2 Spike Glycoprotein (S2)- His-Tag (Insect Cells; yellow line) (Native Antigen) at concentrations of 5 ug/ml. A 3-fold serial dilution from 41.6 ng/ml was performed using 24-805; from 370 ng/ml for 6.0 and from 10000 ng/ml for 5.0 and 1.0. Human IgM- human IgA and human IgG2 were HRP-conjugated and for the detection of human IgG1 a 1:4000 dilution of HRP-lnti-human IgG antibody was used.

Further Information

Additional Names:
Spike protein, COVID19, COVID 19, S protein, SARS-CoV S protein, S glycoprotein, E2, Peplomer protein, Spike protein S1, SARS Coronavirus, SARS-CoV-2, SARS CoV 2, 2019-nCoV
Buffer:
PBS with 0.02% Proclin 300.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
The original monoclonal antibody was generated by sequencing peripheral blood lymphocytes of a patient exposed to the SARS-CoV.
NCBI Gene ID #:
1489668
NCBI Official Name:
spike glycoprotein
NCBI Official Symbol:
S
NCBI Organism:
SARS coronavirus Tor2
Research Area:
Infectious Disease, COVID-19
Swissprot #:
P59594
User NOte:
For research use only.