GITR Antibody [DTA-1], Rabbit IgG
| Code | Size | Price |
|---|
| PSI-24-621-0.2mg | 0.2mg | £681.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Host Type: Rabbit
Antibody Isotype: IgG lambda
Antibody Clonality: Monoclonal
Antibody Clone: DTA-1
Regulatory Status: RUO
Target Species: Mouse
Applications:
- Agonism
- Flow Cytometry
- Immunoprecipitation (IP)
- Western Blot (WB)
Shipping:
Blue Ice
Storage:
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.
Documents
Further Information
Additional Names:
CD357, AITR, GITR-D, Glucocorticoid-induced TNFR-related protein, TNFRSF18, Tumor necrosis factor receptor superfamily member 18
Buffer:
PBS with 0.02% Proclin 300.
Chimeric Use Statement:
This chimeric rabbit antibody was made using the variable domain sequences of the original Rat IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
This antibody was raised by immunising Wistar rats with the CD25+CD4+ T cell line. Hybridoma cells were generated by fusing spleen cells from the immunized rat with P3X63Ag8.653 myeloma cells, assessed for secreting antibodies capable of neutralizing in vitro CD25+CD4+ T cell-mediated suppression of anti-CD3-stimulated T cell proliferation9, and then cloned. This DTA-1 clone secreted a monoclonal rat immunoglobulin G2a (IgG2a) that showed high neutralizing activity.
NCBI Gene ID #:
21936
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 18
NCBI Official Symbol:
Tnfrsf18
NCBI Organism:
Mus musculus
Research Area:
Immunology, Cancer
Swissprot #:
O35714
User NOte:
For research use only.