EGFR Antibody [Matuzumab], Human IgG1

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ProSci
Product Code: PSI-24-425
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-24-425-0.2mg0.2mg£681.00
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Overview

Host Type: Human
Antibody Isotype: IgG1 kappa
Antibody Clonality: Recombinant Antibody
Antibody Clone: Matuzumab
Regulatory Status: RUO
Target Species: Human
Applications:
  • Antagonist
  • Blocking
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
  • Immunofluorescence (IF)
  • Western Blot (WB)
Shipping:
Blue Ice
Storage:
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Images

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<b> Immunohistochemical staining of mouse skin tissue using anti-EGFR antibody (MatuzumAnti-EGFR staining of formaldehyde fixed paraffin embedded mouse skin tissue- at 40x magnification. The human IgG1-chimeric version of Matuzum5) was used to stain samples at a concentration of 5 ug/ml.
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<b> Binding curve of anti-EGFR antibody Matuzum5) to EGFR-Fc fusion protein </b> ELISA Plate coated with human EGFR-Fc (Pr00117-10.9) at a concentration of 5 ug/ml. A 3-fold serial dilution from 100 to 0.1 ng/ml was performed using 24-425. For detection- a 1:4000 dilution of HRP lnti-human kappa light chain antibody was used.
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<b> Immunohistochemical staining of mouse skin tissue using anti-EGFR antibody (MatuzumAnti-EGFR staining of formaldehyde fixed paraffin embedded mouse skin tissue- at 40x magnification. The human IgG1-chimeric version of Matuzum5) was used to stain samples at a concentration of 5 ug/ml.
<b> Binding curve of anti-EGFR antibody Matuzum5) to EGFR-Fc fusion protein </b> ELISA Plate coated with human EGFR-Fc (Pr00117-10.9) at a concentration of 5 ug/ml. A 3-fold serial dilution from 100 to 0.1 ng/ml was performed using 24-425. For detection- a 1:4000 dilution of HRP lnti-human kappa light chain antibody was used.

Documents

Further Information

Additional Names:
ErbB-1, ERBB1, HER1, EGF, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1, EMD72000, mAb425, 425, mAb 425
Buffer:
PBS with 0.02% Proclin 300.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
The parental mouse antibody was generated by immunizing BALB/c mice intraperitoneally with A431 cells in phosphate buffered saline (PBS). Later on the humanzied version of the antibody was created by grafting CDRs of the murine antibody onto human constant regions.
NCBI Gene ID #:
718
NCBI Official Name:
complement C3
NCBI Official Symbol:
C3
NCBI Organism:
Homo sapiens
Research Area:
Cancer, Other, Immunology, Neuroscience
Swissprot #:
P00533
User NOte:
For research use only.