IL-6 receptor Antibody [rhPM-1 (Tocilizumab)], Rabbit IgG

ProSci
Product Code: PSI-24-502
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-24-502-0.2mg0.2mg£681.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG kappa
Antibody Clonality: Recombinant Antibody
Antibody Clone: rhPM-1 (Tocilizumab)
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Inhibition Assay
Shipping:
Blue Ice
Storage:
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Images

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<b> Immunofluorescence staining of fixed U937 cells with anti-IL-6 receptorantibody rhPM-1 (Tocilizum737) </b> Immunofluorescence analysis of paraformaldehyde fixed U937 cells on Shi-fix™ coverslips- permewith 0.15% Triton and stained with the chimeric r version of rhPM-1 (Tocilizum02) at 10 ug/ml for 1h followed by Alexa Fluor®?488 secondary antibody (1 ug/ml)- showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right- top-bottom 24-502- DAPI- merged channels and an isotype control. The isotype control was stained with an anti-Fluorescein antibody (0) followed by Alexa Fluor®?488 secondary antibody.

<b> Immunofluorescence staining of fixed U937 cells with anti-IL-6 receptorantibody rhPM-1 (Tocilizum737) </b> Immunofluorescence analysis of paraformaldehyde fixed U937 cells on Shi-fix™ coverslips- permewith 0.15% Triton and stained with the chimeric r version of rhPM-1 (Tocilizum02) at 10 ug/ml for 1h followed by Alexa Fluor®?488 secondary antibody (1 ug/ml)- showing membrane staining. The nuclear stain is DAPI (blue). Panels show from left-right- top-bottom 24-502- DAPI- merged channels and an isotype control. The isotype control was stained with an anti-Fluorescein antibody (0) followed by Alexa Fluor®?488 secondary antibody.

Further Information

Additional Names:
IL6R, IL-6R, CD126, MRA, atlizumab, TCZ, Interleukin-6 receptor subunit alpha, IL-6 receptor subunit alpha, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL-6R 1, Membrane glycoprotein 80, gp80, PM1, PM-1
Buffer:
PBS with 0.02% Proclin 300.
Chimeric Use Statement:
This chimeric rabbit antibody was made using the variable domain sequences of the original Human IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
The original antibody was generated by CDR grafting of mouse PM-1 antibody onto human REI and NEW framework regions to create rhPM-1.
NCBI Gene ID #:
3570
NCBI Official Name:
HGNC:HGNC:6019
NCBI Official Symbol:
IL6R
NCBI Organism:
Homo sapiens
Research Area:
Other, Cancer
Swissprot #:
P08887
User NOte:
For research use only.