DR5 Antibody [TRA-8], Rabbit IgG

ProSci
Product Code: PSI-24-580
Product Group: Primary Antibodies
Supplier: ProSci
CodeSizePrice
PSI-24-580-0.2mg0.2mg£681.00
Quantity:
Prices exclude any Taxes / VAT

Overview

Host Type: Rabbit
Antibody Isotype: IgG kappa
Antibody Clonality: Monoclonal
Antibody Clone: TRA-8
Regulatory Status: RUO
Target Species: Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Flow Cytometry
  • Western Blot (WB)
Shipping:
Blue Ice
Storage:
Store at 4⁰C for up to 3 months. For longer storage, aliquot and store at -20⁰C.

Images

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<b> Immunofluorescence staining of HepG2 cells using anti-DR5 antibody (TRA-8. </b> Immunofluorescence analysis of paraformaldehyde fixed HepG2 cells stained with the chimeric r version of TRA-8 (24-580) at 10 ug/ml followed by Alexa Fluor® 488 secondary antibody (2 ug/ml)- showing cytoplasmic staining. The nuclear stain is DAPI (blue). Panels show from left-right- top-bottom 24-580- DAPI- merged channels and an isotype control. The isotype control was stained with anti-Fluorescein antibody (3.0) followed by Alexa Fluor® 488 secondary antibody.

<b> Immunofluorescence staining of HepG2 cells using anti-DR5 antibody (TRA-8. </b> Immunofluorescence analysis of paraformaldehyde fixed HepG2 cells stained with the chimeric r version of TRA-8 (24-580) at 10 ug/ml followed by Alexa Fluor® 488 secondary antibody (2 ug/ml)- showing cytoplasmic staining. The nuclear stain is DAPI (blue). Panels show from left-right- top-bottom 24-580- DAPI- merged channels and an isotype control. The isotype control was stained with anti-Fluorescein antibody (3.0) followed by Alexa Fluor® 488 secondary antibody.

Further Information

Additional Names:
TRAILR2, TNFRSF10B, TRAIL receptor 2, tumor necrosis factor receptor superfamily member 10B
Buffer:
PBS with 0.02% Proclin 300.
Chimeric Use Statement:
This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
The antibody was raised by immunizing BALB/c mice with a fusion protein containing the extracellular portion of human DR5 and the Fc portion of human IgG1.
NCBI Gene ID #:
8795
NCBI Official Name:
TNF receptor superfamily member 10b
NCBI Official Symbol:
TNFRSF10B
NCBI Organism:
Homo sapiens
Research Area:
Cancer, Apoptosis, Cell Cycle
Swissprot #:
O14763
User NOte:
For research use only.