ZC3H12A (CT) Peptide
| Code | Size | Price |
|---|
| PSI-9547P-0.05mg | 0.05mg | £166.00 |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Application: Blocking
Shipping:
Blue Ice
Storage:
Store SARS-CoV-2 (COVID-19) Spike Q493R G496S Q498R N501Y Y505H Peptide (Omicron) at -20˚C, stable for one year.
Documents
Further Information
Additional Names:
ZC3H12A Antibody: Endoribonuclease ZC3H12A, Monocyte chemotactic protein-induced protein 1, MCP-induced protein 1, MCPIP-1, Zinc finger CCCH domain-containing protein 12A
Application Note:
ZC3H12A (CT) Peptide is used for blocking the activity of ZC3H12A (CT) Antibody.
Background:
ZC3H12A Antibody: ZC3H12A is an MCP1 (CCL2; MIM 158105)-induced protein that acts as a transcriptional activator and causes cell death of cardiomyocytes, possibly via induction of genes associated with apoptosis. ZC3H12A inhibits the Wnt/beta-catenin signaling pathway activity and modulates epithelial-mesenchymal transition during clear cell renal cell carcinoma progression by targeting miRNAs. ZC3H12A ribonuclease can bind and cleave AURKA mRNA in MYCN-amplified neuroblastoma cells. ZC3H12A is a novel link between diabetogenic conditions and impaired insulin secretory capacity. ZC3H12A overexpression in human neuroblastoma cell lines causes cell-cycle arrest by G1/S checkpoint block.
Background References:
- Gorka et al. Oncogene. 2021; 40(50):6720-6735
- Nowak et al. RNA Biol. 2021; 18(1):144-156
- Tyka et al. Biochim Biophys Acta Mol Basis Dis. 2021; 1867(10):166199
- Boratyn et al. J Cell Biochem. 2020; 121(5-6);3406-3425
Buffer:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Concentration:
200 ug/mL
NCBI Gene ID #:
80149
NCBI Official Name:
zinc finger CCCH-type containing 12A
NCBI Official Symbol:
ZC3H12A
NCBI Organism:
Homo sapiens
Peptide aa Location:
14 amino acids near the carboxyl terminus of human ZC3H12A.
Physical State:
Liquid
Protein Accession #:
Q5D1E7.2
Protein GI Number:
190485853
Swissprot #:
Q5D1E8
User Note:
Optimal dilutions for each application to be determined by the researcher.