24R-Calcipotriol

TargetMol
Product Code: TAR-T10088
Supplier: TargetMol
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TAR-T10088-10mg10mgEnquire
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TAR-T10088-5mg5mgEnquire
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TAR-T10088-1mg1mg£408.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
24R-Calcipotriol(PRI 2202) is an impurity of Calcipotriol which is a ligand of VDR-like receptors.
CAS:
112827-99-3
Formula:
C27H40O3
Molecular Weight:
412.614
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H]([C@H](C)C=C[C@H](O)C3CC3)[C@@]1(C)CCCC2=C/C=C1/C[C@@H](O)C[C@H](O)C1=C

References

1. Gocek, Elzbieta; Kielbinski, Marek; Baurska, Hanna et al. Different susceptibilities to 1,25-dihydroxyvitamin D3-induced differentiation of AML cells carrying various mutations. Leukemia Research (2010), 34(5), 649-657. 2. Gocek, Elzbieta; Kielbinski, Marek; Wylob, Paulina et al. Side-chain modified vitamin D analogs induce rapid accumulation of VDR in the cell nuclei proportionately to their differentiation-inducing potential. Steroids (2008), 73(14), 1359-1366. 3. Wietrzyk, Joanna; Nevozhay, Dmitry; Filip, Beata et al. The antitumor effect of lowered doses of cytostatics combined with new analogs of vitamin D in mice. Anticancer Research (2007), 27(5A), 3387-3398. 4. Wietrzyk, Joanna; Chodynski, Michal; Fitak, Hanna et al. Antitumor properties of diastereomeric and geometric analogs of vitamin D3. Anti-Cancer Drugs (2007), 18(4), 447-457.