ACHP Hydrochloride

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TargetMol
Product Code: TAR-T10237
Supplier: TargetMol
CodeSizePrice
TAR-T10237-1mg1mg£130.00
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TAR-T10237-5mg5mg£214.00
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TAR-T10237-1mL1 mL * 10 mM (in DMSO)£230.00
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TAR-T10237-10mg10mg£306.00
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TAR-T10237-25mg25mg£462.00
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TAR-T10237-50mg50mg£629.00
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TAR-T10237-100mg100mg£870.00
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TAR-T10237-500mg500mg£1,669.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
ACHP Hydrochloride is a highly potent and selective IKK-β inhibitor with an IC50 of 8.5 nM.
CAS:
406209-26-5
Formula:
C21H25ClN4O2
Molecular Weight:
400.91
Pathway:
NF-κb
Purity:
0.98
SMILES:
Cl.Nc1nc(cc(C2CCNCC2)c1C#N)-c1c(O)cccc1OCC1CC1
Target:
IκB/IKK

References

1. Murata T, et al. Synthesis and structure-activity relationships of novel IKK-beta inhibitors. Part 3: Orally active anti-inflammatory agents. Bioorg Med Chem Lett. 2004 Aug 2;14(15):4019-22. 2. Sanda T, et al. Induction of cell death in adult T-cell leukemia cells by a novel IkappaB kinase inhibitor. Leukemia. 2006 Apr;20(4):590-8.