AT-007

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TargetMol
Product Code: TAR-T10393
Supplier: TargetMol
CodeSizePrice
TAR-T10393-1mg1mg£129.00
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TAR-T10393-5mg5mg£197.00
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TAR-T10393-1mL1 mL * 10 mM (in DMSO)£209.00
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TAR-T10393-10mg10mg£270.00
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TAR-T10393-25mg25mg£442.00
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TAR-T10393-50mg50mg£619.00
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TAR-T10393-100mg100mg£852.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prevents disease complications in GALT deficiency rats.
CAS:
2170729-29-8
Formula:
C17H10F3N3O3S2
Molecular Weight:
425.4
Pathway:
Endocrinology/Hormones; Metabolism
Purity:
0.9936
SMILES:
OC(=O)Cc1nn(Cc2nc3cc(ccc3s2)C(F)(F)F)c(=O)c2cscc12
Target:
Reductase

References

1. Maeve Conneighton, et al. Applied Therapeutics Announces Initiation of Phase 1/2 Study of AT-007 in Galactosemia. 2. UNITED STATES SECURITIES AND EXCHANGE COMMISSION. APPLIED THERAPEUTICS, INC.