D8-MMAD

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TargetMol
Product Code: TAR-T10947
Supplier: TargetMol
CodeSizePrice
TAR-T10947-100mg100mgEnquire
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TAR-T10947-50mg50mgEnquire
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TAR-T10947-1mg1mg£850.00
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TAR-T10947-5mg5mg£1,839.00
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TAR-T10947-1mL1 mL * 10 mM (in DMSO)£2,919.00
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TAR-T10947-10mg10mg£3,393.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
D8-MMAD is a deuterated form of MMAD, which is a microtubule destroyer.
CAS:
T10947
Formula:
C41H58D8N6O6S
Molecular Weight:
779.11
Purity:
0.98
SMILES:
O=C(N[C@H](C1=NC=CS1)CC2=CC=CC=C2)[C@H](C)[C@@H](OC)[C@H]3N(C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C([C@@](C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])([2H])NC([C@H](C(C)C)NC)=O)=O)C)=O)CCC3

References

1. Chudasama V, et al. Recent advances in the construction of antibody-drug conjugates. Nat Chem. 2016 Feb;8(2):114-9.