TargetMol

DW14800

Product Code:
 
TAR-T11131
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T11131-1mg1mg£142.00
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TAR-T11131-2mg2mg£177.00
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TAR-T11131-5mg5mg£254.00
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TAR-T11131-1mL1 mL * 10 mM (in DMSO)£278.00
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TAR-T11131-10mg10mg£389.00
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TAR-T11131-25mg25mg£677.00
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TAR-T11131-50mg50mg£871.00
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TAR-T11131-100mg100mg£1,267.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.
CAS:
2243709-60-4
Formula:
C31H36N4O3
Molecular Weight:
512.64
Pathway:
Chromatin/Epigenetic
Purity:
0.9912
SMILES:
CN(C)c1ccc(cc1)C(=O)N1CCc2cc(ccc2C1)C(=O)NCC(O)CN1CCc2ccccc2C1
Target:
Histone Methyltransferase

References

1. Zheng BN, et al. Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4?. Theranostics. 2019 Apr 13;9(9):2606-2617.