GET73

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TargetMol
Product Code: TAR-T11393
Supplier: TargetMol
CodeSizePrice
TAR-T11393-1mg1mg£173.00
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TAR-T11393-5mg5mg£289.00
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TAR-T11393-1mL1 mL * 10 mM (in DMSO)£386.00
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TAR-T11393-10mg10mg£422.00
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TAR-T11393-25mg25mg£651.00
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TAR-T11393-50mg50mg£863.00
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TAR-T11393-100mg100mg£1,179.00
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TAR-T11393-500mg500mg£2,287.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
GET73 is an negative allosteric modulator of mGluR5. GET73 is a naturally occurring neurotransmitter. GET73 has anti-alcohol and anxiolytic properties.
CAS:
202402-01-5
Formula:
C13H16F3NO2
Molecular Weight:
275.271
Pathway:
Neuroscience
Purity:
0.9954
SMILES:
COCCCC(=O)NCc1ccc(cc1)C(F)(F)F
Target:
GluR

References

1. Tomasini MC, et al. GET73 Prevents Ethanol-Induced Neurotoxicity in Primary Cultures of Rat Hippocampal Neurons. Alcohol Alcohol. 2016 Mar;51(2):128-35. 2. Ferraro L, et al. GET73 modulates rat hippocampal glutamate transmission: evidence for a functional interaction with mGluR5. Pharmacol Rep. 2011;63(6):1359-71. 3. Loche A, et al. Anti-Alcohol and Anxiolytic Properties of a New Chemical Entity, GET73. Front Psychiatry. 2012 Feb 14;3:8.