KAN0438757

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TargetMol
Product Code: TAR-T11741
Supplier: TargetMol
CodeSizePrice
TAR-T11741-1mg1mg£153.00
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TAR-T11741-5mg5mg£233.00
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TAR-T11741-1mL1 mL * 10 mM (in DMSO)£245.00
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TAR-T11741-10mg10mg£330.00
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TAR-T11741-25mg25mg£539.00
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TAR-T11741-50mg50mg£714.00
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TAR-T11741-100mg100mg£946.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
KAN0438757 is a selective and potent inhibitor of the metabolic kinase PFKFB3 with an IC50 of 0.19 μM.
CAS:
1451255-59-6
Formula:
C21H18FNO7S
Molecular Weight:
447.43
Pathway:
Autophagy; Metabolism
Purity:
0.998
SMILES:
OCCOC(=O)c1ccc(NS(=O)(=O)c2cccc(c2)-c2cc(F)ccc2O)cc1O
Target:
Glucokinase; Autophagy

References

1. Gustafsson NMS, et al. Targeting PFKFB3 radiosensitizes cancer cells and suppresses homologous recombination. Nat Commun. 2018 Sep 24;9(1):3872.