Navitoclax-piperazine

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TargetMol
Product Code: TAR-T12186
Supplier: TargetMol
CodeSizePrice
TAR-T12186-1mg1mg£197.00
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TAR-T12186-5mg5mg£331.00
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TAR-T12186-10mg10mg£512.00
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TAR-T12186-1mL1 mL * 10 mM (in DMSO)£520.00
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TAR-T12186-25mg25mg£768.00
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TAR-T12186-50mg50mg£1,026.00
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TAR-T12186-100mg100mg£1,364.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Navitoclax-piperazine is an inhibitor of B-cell lymphoma extra large (BCL-XL).
CAS:
2143096-93-7
Formula:
C47H56ClF3N6O5S3
Molecular Weight:
973.63
Pathway:
Apoptosis
Purity:
0.9982
SMILES:
CC1(C)CCC(=C(CN2CCN(CC2)c2ccc(cc2)C(=O)NS(=O)(=O)c2ccc(N[C@H](CCN3CCNCC3)CSc3ccccc3)c(c2)S(=O)(=O)C(F)(F)F)C1)c1ccc(Cl)cc1
Target:
BCL

References

1. Sajid Khan, et al. A selective BCL-XL PROTAC degrader achieves safe and potent antitumor activity. Nat Med 25, 1938?1947 (2019).