NTP42

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TargetMol
Product Code: TAR-T12268
Supplier: TargetMol
CodeSizePrice
TAR-T12268-1mg1mg£116.00
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TAR-T12268-2mg2mg£137.00
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TAR-T12268-5mg5mg£185.00
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TAR-T12268-1mL1 mL * 10 mM (in DMSO)£201.00
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TAR-T12268-10mg10mg£252.00
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TAR-T12268-25mg25mg£378.00
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TAR-T12268-50mg50mg£528.00
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TAR-T12268-100mg100mg£726.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
NTP42 is an antagonist of thromboxane A2 (TXA2) receptor(IC50 of 3.278 nM)
CAS:
2055599-51-2
Formula:
C25H23F2N3O5S
Molecular Weight:
515.53
Pathway:
GPCR/G Protein; Metabolism; DNA Damage/DNA Repair; Immunology/Inflammation
Purity:
0.9909
SMILES:
CC(C)(C)NC(=O)NS(=O)(=O)c1cc(ccc1Oc1cccc(c1)-c1ccc(OC(F)F)cc1)C#N
Target:
Prostaglandin Receptor; PPAR

References

1. B. Therese KINSELLA, et al. Thromboxane receptor antagonists. WO2016203314A1. 2. Eamon Mulvaney, et al. NTP42, a novel antagonist of the thromboxane receptor, attenuates experimentally induced pulmonary arterial hypertension.