p38- α MAPK-IN-1

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TargetMol
Product Code: TAR-T12347
Supplier: TargetMol
CodeSizePrice
TAR-T12347-1mg1mg£149.00
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TAR-T12347-5mg5mg£275.00
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TAR-T12347-1mL1 mL * 10 mM (in DMSO)£287.00
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TAR-T12347-10mg10mg£402.00
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TAR-T12347-25mg25mg£626.00
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TAR-T12347-50mg50mg£862.00
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TAR-T12347-100mg100mg£1,139.00
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TAR-T12347-500mg500mg£2,207.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
p38-α MAPK-IN-1 is a MAPK14 (p38-α) inhibitor with IC50 of 2300 nM and 5500 nM in EFC displacement assay and HTRF assay,respectively.
CAS:
443913-15-3
Formula:
C27H35N5O3
Molecular Weight:
477.609
Pathway:
MAPK; Autophagy
Purity:
0.9952
SMILES:
Cc1ccc(cc1)-n1nc(cc1NC(=O)Nc1ccc(OCCN2CCOCC2)cc1)C(C)(C)C
Target:
p38 MAPK; Autophagy

References

1. Kluter S, et al. Displacement assay for the detection of stabilizers of inactive kinase conformations. J Med Chem. 2010 Jan 14;53(1):357-67.