(Rac)-BRD0705

TargetMol
Product Code: TAR-T12664
Supplier: TargetMol
CodeSizePrice
TAR-T12664-1mg1mg£189.00
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Quantity:
TAR-T12664-1mL1 mL * 10 mM (in DMSO)£281.00
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Quantity:
TAR-T12664-5mg5mg£369.00
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Quantity:
TAR-T12664-10mg10mg£517.00
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Quantity:
TAR-T12664-25mg25mg£790.00
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Quantity:
TAR-T12664-50mg50mg£1,050.00
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Quantity:
TAR-T12664-100mg100mg£1,396.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
(Rac)-BRD0705 is a less active racemate of BRD0705. BRD0705 is an effective and selective inhibitor of GSK3α.
CAS:
1597440-03-3
Formula:
C20H23N3O
Molecular Weight:
321.424
Purity:
0.98
SMILES:
CCC1(C2=CNNC2=NC2=C1C(=O)CC(C)(C)C2)c1ccccc1

References

1. Edward Scolnick, et al. Uses of paralog-selective inhibitors of gsk3 kinases. US20160375006A1. 2. Wagner FF, et al. Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Sci Transl Med. 2018 Mar 7;10(431). pii: eaam8460.