RORγt Inverse agonist 6

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TargetMol
Product Code: TAR-T12753
Supplier: TargetMol
CodeSizePrice
TAR-T12753-1mg1mg£197.00
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TAR-T12753-5mg5mg£389.00
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TAR-T12753-1mL1 mL * 10 mM (in DMSO)£466.00
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TAR-T12753-10mg10mg£544.00
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TAR-T12753-25mg25mg£830.00
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TAR-T12753-50mg50mg£1,099.00
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TAR-T12753-100mg100mg£1,460.00
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TAR-T12753-500mg500mg£2,850.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
RORγt Inverse agonist 6 is an agonist of RORγt inverse. RORγt Inverse agonist 6 can be used in research on Th17-driven autoimmune diseases.
CAS:
1887161-80-9
Formula:
C28H29ClN6O5
Molecular Weight:
565.03
Pathway:
Metabolism
Purity:
0.98
SMILES:
CC(C)n1c2ccc(NC(=O)N3CCO[C@H](C3)C(=O)Nc3ccc(C#N)c(Cl)c3)cc2c(=O)n(CC2CC2)c1=O
Target:
ROR

References

1. Sato A, et al. Design and Synthesis of Conformationally Constrained ROR?t Inverse Agonists. ChemMedChem. 2019 Oct 28.