TargetMol

Penicillic acid

Product Code:
 
TAR-T13815
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T13815-1mg1mg£118.00
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Quantity:
TAR-T13815-1mL1 mL * 10 mM (in DMSO)£180.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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Further Information

Bioactivity:
Penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8.Penicillic acid is a polyketide mycotoxin produced by several species of Aspergillus and Penicillium. Penicillic acid exhibits cytotoxicity in rat alveolar macrophages (AM) in vitro.
CAS:
90-65-3
Formula:
C8H10O4
Molecular Weight:
170.164
Pathway:
Microbiology/Virology; Apoptosis; Proteases/Proteasome
Purity:
0.98
SMILES:
COC(=C/C(O)=O)C(=O)C(C)=C
Target:
Apoptosis; Caspase; Antibacterial; Antibiotic

References

1. Sorenson WG, et al. Toxicity of penicillic acid for rat alveolar macrophages in vitro. Environ Res. 1986 Dec;41(2):505-13. 2. Bando M, et al. The mycotoxin penicillic acid inhibits Fas ligand-induced apoptosis by blocking self-processing of caspase-8 in death-inducing signaling complex. J Biol Chem. 2003 Feb 21;278(8):5786-93.