UCB-9260

TargetMol
Product Code: TAR-T13951
Supplier: TargetMol
CodeSizePrice
TAR-T13951-1mg1mg£149.00
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TAR-T13951-5mg5mg£266.00
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Quantity:
TAR-T13951-1mL1 mL * 10 mM (in DMSO)£289.00
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Quantity:
TAR-T13951-10mg10mg£396.00
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TAR-T13951-25mg25mg£613.00
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TAR-T13951-50mg50mg£843.00
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Quantity:
TAR-T13951-100mg100mg£1,099.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
UCB-9260 inhibits TNF signaling by stabilizing an asymmetric form of the trimer.
CAS:
1515888-53-5
Formula:
C26H25N5O
Molecular Weight:
423.52
Pathway:
Apoptosis
Purity:
0.9965
SMILES:
Cc1ccc(C)c(Cn2c(nc3ccc(cc23)-c2cnn(C)c2)C(O)c2ccncc2)c1
Target:
TNF

References

1. O'Connell J, et al.Small?molecules?that?inhibit?TNF?signalling?by?stabilising?an?asymmetric?form?of the?trimer.Nat Commun.?2019 Dec 19;10(1):5795.