4E2RCat

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TargetMol
Product Code: TAR-T14044
Supplier: TargetMol
CodeSizePrice
TAR-T14044-1mg1mg£148.00
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TAR-T14044-5mg5mg£333.00
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Quantity:
TAR-T14044-1mL1 mL * 10 mM (in DMSO)£334.00
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Quantity:
TAR-T14044-10mg10mg£470.00
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Quantity:
TAR-T14044-25mg25mg£707.00
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TAR-T14044-50mg50mg£978.00
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Quantity:
TAR-T14044-100mg100mg£1,291.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
4E2RCat is an inhibitor of eIF4E-eIF4G interaction (IC50 = 13.5 μM) and is capable of blocking coronavirus replication as monitored by viral protein expression and the production of infectious virus.
CAS:
432499-63-3
Formula:
C22H14ClNO4S2
Molecular Weight:
455.93
Pathway:
Apoptosis
Purity:
0.98
SMILES:
OC(=O)c1cc(ccc1Cl)-c1ccc(C=C2/SC(=S)N(Cc3ccccc3)C2=O)o1
Target:
PERK

References

1. Cencic R, et al. Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. J Virol. 2011 Jul;85(13):6381-9.