Fumitremorgin C
Code | Size | Price |
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TAR-T15355-1mg | 1mg | £261.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Fumitremorgin C is a mycotoxin and inhibits ABCG2/BRCP.
CAS:
118974-02-0
Formula:
C22H25N3O3
Molecular Weight:
379.46
Pathway:
Membrane transporter/Ion channel; Microbiology/Virology
Purity:
0.98
SMILES:
[H][C@@]12CCCN1C(=O)[C@]1([H])Cc3c([nH]c4cc(OC)ccc34)[C@]([H])(C=C(C)C)N1C2=O
Target:
BCRP; Antibacterial; Antibiotic; ABC
References
1. Rabindran SK, et al. Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C. Cancer Res. 1998 Dec 15;58(24):5850-8.
2. Rabindran SK, et al. Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein. Cancer Res. 2000 Jan 1;60(1):47-50.