GNF179

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TargetMol
Product Code: TAR-T15409
Supplier: TargetMol
CodeSizePrice
TAR-T15409-1mg1mg£179.00
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TAR-T15409-5mg5mg£303.00
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TAR-T15409-1mL1 mL * 10 mM (in DMSO)£326.00
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TAR-T15409-10mg10mg£454.00
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TAR-T15409-25mg25mg£704.00
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TAR-T15409-50mg50mg£938.00
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TAR-T15409-100mg100mg£1,259.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
GNF179 is an optimized 8,8-dimethyl IP analog. It exhibited the potency(4.8 nM against the multidrug resistant strain W2) in vitro metabolic stability and in vivo oral bioavailability.
CAS:
1261114-01-5
Formula:
C22H23ClFN5O
Molecular Weight:
427.91
Pathway:
Microbiology/Virology
Purity:
0.989
SMILES:
CC1(C)N(CCn2c(Nc3ccc(Cl)cc3)c(nc12)-c1ccc(F)cc1)C(=O)CN
Target:
Parasite

References

1. Meister S, et al. Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery. Science. 2011 Dec 9;334(6061):1372-7.